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Exciting isekai anime like The Greatest Alchemist of All Time focuses on transformation and powerful protagonists.
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When I Was Reincarnated as a Slime features an overwhelming protagonist changing the world.
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By the Grace of the Gods and The Rising of the Shield Hero explore themes of personal growth and redemption.
In the ever-expanding world of isekai, stories about protagonists seeking a quiet life away from conquest and battle have become all too common. Perhaps the greatest alchemist of all time. It starts off in this direction, but as the protagonist unknowingly chooses the most powerful skills, his journey evolves into a complex path full of possibilities.

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7 Best Isekai Anime with Inspiring Hero's Journeys, Ranked
Most isekai begin on a relatively similar note, involving arrival in a new world. The series follows that moment in an inspiring hero's journey.
This exciting story captures the essence of change and highlights the powerful challenge of staying true to your values. Next is Probably the best isekai anime like The Greatest Alchemist of all time. For fans of the series who want an experience that mixes self-discovery, heartwarming moments, and adventure.
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At that time I was reincarnated as a slime
A series about creating your destiny and accepting life's challenges.
- release date
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October 5, 2018
- studio
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8 bit
- creator
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fuse
Satoru Mikami, an ordinary office worker, is reincarnated in a fantasy world as a lump of slime after succumbing to a senseless incident of violence. Equipped with the ability to mimic the power of all he devours, he undergoes a dramatic transformation that changes not only his own fate, but that of the new world as well.
It's simple. I want to create a world where life is as convenient as you want. A comfortable world where everyone can laugh and have fun to their heart’s content. That's what I truly and honestly want.
At that time I was reincarnated as a slimeLike perhaps the greatest alchemist of all time, this is an exciting isekai series that focuses on an overpowering protagonist who embarks on a life-changing adventure and wisely uses his newfound powers to reshape the world. Both anime revolve around themes such as personal growth, creating lasting change, and making the most of life's unexpected challenges.
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by the grace of the gods
A show about second chances
by the grace of the gods It tells the story of Ryoma Takebayashi, a child who, after enduring a harsh and lonely life in his final life, was blessed by God and tasted the wonders of life. He spends several years enjoying solitude away from civilization, but after experiencing a series of events, he eventually sets off on a journey beyond his hometown. Like Iruma, Ryoma's adventures give him a sense of accomplishment and lead to meaningful connections that change his life.
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Resurrection of the Shield Hero
The story of an otaku who became a savior
Resurrection of the Shield Hero
- release date
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January 9, 2019
- studio
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Kinema Citrus, DR Movie
- creator
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Yusagi Aneko
Naofumi Iwatani is an otaku who is one of four heroes selected from modern Japan to save the Kingdom of Melomac in another world. However, soon after arriving in the New World, the situation worsens as the young hero is considered the weakest by his peers because he is only given a shield, and to make matters worse, he is later falsely accused of assault. He is out of favor with the public.
I wanted the whole place, the whole world, to be reduced to ashes.
rise of the shield Although the hero is shunned by society, he fulfills his duty as a hero and follows Naofumi to save himself. If you're an anime fan of arguably the greatest alchemist of all time, The Rising of the Shield Hero will appeal. Because it follows Naofumi's journey as he overcomes adversity, builds alliances, and grows into a nearly invincible hero like Takumi.
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Death March to the Parallel World Rhapsody
The story of a programmer trapped in the game world
Death March to the Parallel World Rhapsody
- release date
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January 11, 2018
- studio
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Silver Link, connection
- creator
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Ainana Hiro
Death March to the Parallel World Rhapsody Fans of The Greatest Alchemist of All Time looking for an isekai series with an overpowering protagonist might be interested. The show centers around a programmer named Ichiro Suzuki who is transported to a mysterious RPG world.

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Ranking of the best isekai anime where the protagonist utilizes modern knowledge
Many isekai anime have proven that having modern knowledge can definitely be beneficial.
There, Suzuki embarks on an epic adventure and discovers that he has been imbued with the powers of a high-level adventurer, enabling him to win epic battles against fearsome foes. Thrilled by the experiences his new life brings, Ichirou sets out to explore a magical world full of wonder and danger.
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Farming life in another world
Isekai series depicting a terminally ill patient receiving God's blessing
Farming life in another world
- release date
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January 6, 2023
- streaming service
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cryptic
- studio
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weightlessness
- creator
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Naito Kinosuke
Naito Kinosuke Farming life in another world This is the story of an ordinary man whose sudden death gives God another chance to live his life on his own terms. Given an all-purpose farming tool, he is reincarnated in another world and uses his newfound powers to cultivate a peaceful and satisfying life. Like Takumi Iruma, the protagonist finds meaning in life and new passion by using his abilities for the greater good, changing the fate of those around him in the process.
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Cooking over a campfire in another world with my absurd skills
The story of a salaryman chosen as a hero
Cooking over a campfire in another world with my absurd skills
- release date
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January 11, 2023
- Author
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Eguchi Ren
Tsuyoshi Mukouda, an ordinary office worker, is a person whose life changes dramatically when he is summoned to another world as a hero. With his strange skills as an online supermarket, Mukouda soon seems like an unsuitable candidate to lead the Reijseger Kingdom's combat activities. However, his powers eventually proved invaluable as he was used to bring luxurious tools from Japan. Tsuyoshi's delicious cooking soon won him recognition and allowed him to make a pact with the mythical wolf Fel.
I had no interest in hunting giant beasts, but my familiars were such dedicated combat junkies that they would never miss an opportunity to hunt them.
As Mukouda's fate takes an unprecedented turn, he uses his situation as an opportunity to embark on an adventure around the world. If you like The Greatest Alchemist of All Time and would like to see another isekai anime where the protagonist uses unconventional skills to succeed in a fantasy world, consider adding it. Campfire cuisine from another world Add My Absurd Skill to your watchlist.
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Travel to another world: Raising children on adventure
The story of an unexpected adventurer
Travel to another world: Raising children on adventure
- release date
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July 7, 2024
- studio
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EMT Squared, Brothers Bird
- creator
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Minazuki Shizuru
Like Takumi Iruma, who may be the greatest alchemist of all time, Takumi Kayano is transported to a fantasy world after an accident involving the wind god Silpilil. Gifted with newfound powers, Kayano was born in the dangerous forest of Gaia. There, he meets and becomes friends with five-year-old twins Alan and Elena, who have incredible physical strength that defies logic.

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10 isekai anime that kill off important characters
This series demonstrates that isekai series can effectively incorporate the deaths of important characters to enhance emotional engagement and plot.
Unaware of what the fantasy world has in store for them, the three embark on an epic adventure that will not only change their lives, but dramatically alter the fate of the world they live in. Travel to another world: Raising children on adventure is an exciting isekai series, perhaps as good as The Greatest Alchemist of All Time, featuring a protagonist who, despite being the victim of an accident, turns his situation into an opportunity for growth and adventure.

Perhaps the greatest alchemist of all time.
- release date
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January 1, 2025
- studio
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studio comet
- creator
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Kogitsunemaru